Article

Causal inference for multiple risk factors and diseases from genomics data

2023-12-08

Abstract excerpt

Statistical causal learning in genome-wide association studies (GWAS) relies on the instrumental variable method of Mendelian Randomization (MR). Currently, an over-whelming number of MR studies purport to show causal relationships among a wide range of risk factors and outcomes. Here, we find that naive application of many recently proposed MR approaches results in numerous null relationships being discovered as...

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Literature Corpus work: bd0953ee-2cde-5603-9e3e-a314d17ec551
DOI: 10.1101/2023.12.06.570392

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