Article

Improving fusion call confidence and reliability through an optimized process in low quality RNA from formalin-fixed, paraffin-embedded samples

2023-08-02

Abstract excerpt

<title>Abstract</title> <p>Identifying fusion genes in solid tumors is crucial for precision diagnosis and treatment of cancer patients. However, poor RNA quality may pose a major challenge to the reliability of fusion detection. In this study, an optimized RNA fusion detection method using targeted next-generation sequencing was developed and validated to detect gene fusions in solid tumors using formalin-fixed,...

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Literature Corpus work: bd08635d-f20c-5068-8ad3-3aa4943d62fb
DOI: 10.21203/rs.3.rs-3211852/v1

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