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Critical assay parameters facilitating confident detection of expression changes, fusions and short variants in RNA isolated from tissue

2024-11-03

Abstract excerpt

<h4>ABSTRACT</h4> Molecular assays based on next-generation sequencing of RNA can provide clinically relevant information by measuring gene expression levels, identifying gene fusions, aberrant transcript isoforms and detecting small variants. Nevertheless, achieving good performance and reliable result interpretation present a significant challenge. In this work, we dissect the impact of various technical factor...

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Literature Corpus work
fcf2bda0-207a-5920-9d4f-865c51978c39
DOI
10.1101/2024.10.30.621018
Open publication

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Critical assay parameters facilitating confident detection of expression changes, fusions and short variants in RNA isolated from tissueDOI 10.1101/2024.10.30.621018
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