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Gene Fusion Identification Using Anchor-Based Multiplex PCR and Next-Generation Sequencing

1 Dec 2020

Abstract excerpt

BACKGROUND: Methods for identifying gene fusion events, such as fluorescence in situ hybridization (FISH), immunohistochemistry (IHC), and transcriptome analysis, are either single gene approaches or require bioinformatics expertise not generally available in clinical laboratories. We analytically validated a customized next-generation sequencing (NGS) panel targeting fusion events in 34 genes involving...

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PMID: 33537766
DOI: 10.1093/jalm/jfaa230

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