Article

JuLI: accurate detection of DNA fusions in clinical sequencing for precision oncology

2019-01-16

Abstract excerpt

<h4>ABSTRACT</h4> Accurate detection of genomic fusions by high-throughput sequencing in clinical samples with inadequate tumor purity and formalin-fixed paraffin embedded (FFPE) tissue is an essential task in precise oncology. We developed the fusion detection algorithm Junction Location Identifier (JuLI) for optimization of high-depth clinical sequencing. We implemented novel filtering steps to minimize false p...

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Literature Corpus work: 275a45fc-d6bb-5ee2-9c6e-58eb382feba7
DOI: 10.1101/521039

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