Article

Uncovering the heterogeneity of pancreatic endothelial cells using integrative and comparative single cell gene expression analysis

2023-04-20

Abstract excerpt

The pancreatic islet vasculature displays tissue-specific physiological and functional adaptations that support rapid glucose sensing and insulin response by β-cells. To uncover the transcriptomic basis of this specialization, we performed a meta-analysis of multi-organ single cell RNA sequencing atlases employing a unique strategy to avoid transcriptomic contamination. We identified biologically relevant genes in...

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Literature Corpus work: bcf121ba-0fcb-5729-b69b-b0f16c384b32
DOI: 10.1101/2023.04.19.537540

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