Article

Modulation of circadian rhythms in articular cartilage by heat pulses

2024-01-26

Abstract excerpt

<h4>Objective</h4> Prior studies have shown that disruption of the circadian clock leads to cartilage degeneration in mice while shift work is associated with higher risk of osteoarthritis (OA) in humans. In this study we investigated the potential of heat pulses to restore dampened circadian rhythms in articular cartilage. <h4>Methods</h4> Femoral head cartilage explants and primary chondrocytes were isolated f...

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Literature Corpus work: 5f828b76-231a-5603-930d-c2044d603364
DOI: 10.1101/2024.01.26.577368

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