Article

Improving genetic risk modeling of dementia from real-world data in underrepresented populations

2024-02-06

Abstract excerpt

<h4>BACKGROUND</h4> Genetic risk modeling for dementia offers significant benefits, but studies based on real-world data, particularly for underrepresented populations, are limited. <h4>METHODS</h4> We employed an Elastic Net model for dementia risk prediction using single-nucleotide polymorphisms prioritized by functional genomic data from multiple neurodegenerative disease genome-wide association studies. We com...

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Literature Corpus work: bcc75a1a-b4e7-5186-b191-20a2a51799d3
DOI: 10.1101/2024.02.05.24302355

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