Article
Development of a risk prediction model for Alzheimer's disease based on the UK Biobank prospective study.
Journal of Alzheimer's disease : JAD - 1 Nov 2025
Li Huilin, Wu Yiwen, Huang Ting, Sun Yue, Lu Zixuan, Li Musu, Wo Hongmei, Shao Fang, Tang Shaowen, Zhao Yang, Dai Juncheng, Yi Honggang, The Alzheimer's Disease Neuroimaging Initiative
Abstract excerpt
BackgroundEarly prevention and intervention for Alzheimer's disease (AD) are critical due to the absence of effective therapeutic treatment. However, a widely accepted risk prediction model for AD has yet to be established.ObjectiveTo develop a novel risk prediction model for AD by leveraging recent advances in identifying risk factors, focusing on multi-omics data.MethodsGenetic data from the UK Biobank were...
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