Article
Advancing Human Population Genomics with DNA Foundation Models
2025-11-10
Abstract excerpt
<title>Abstract</title> <p> DNA foundation models offer a new approach to interpret genetic variation, but their potential in population-scale genomics remains untapped. We introduce a novel analytical framework that integrates a genomic foundation model with human population genomics studies. We employed the Evo2 DNA foundation model to systematically score the functional impact of a variant and haplotype acros...
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Identifiers and source
- Literature Corpus work
- 07c19162-a1b4-526b-9176-8309f3d14485
- DOI
- 10.21203/rs.3.rs-7889315/v1