Article

Vpr R36w and R77Q Mutations Alter HIV-1 Replication and Cytotoxicity in T Lymphocytes

2020-11-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Acquired immunodeficiency syndrome (AIDS) is caused when HIV depletes CD4+ helper T cell levels in infected patients. Distinct AIDS development rates have shown that there are Rapid Progressor (RP) and Long-Term Non-Progressor (LTNP) patients, but the circumstances governing these differences in the kinetics of helper T cell depletion are poorly understood. Muta...

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Literature Corpus work: bcc4c7b6-7e56-5fd5-a519-f48f78aca54a
DOI: 10.21203/rs.3.rs-107662/v1

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