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Article

HIV-1 Vprâ€”a still â€œenigmatic multitaskerâ€

31 Mar 2014

Abstract excerpt

Like other HIV-1 auxiliary proteins, Vpr is conserved within all the human (HIV-1, HIV-2) and simian (SIV) immunodeficiency viruses. However, Vpr and homologous HIV-2, and SIV Vpx are the only viral auxiliary proteins specifically incorporated into virus particles through direct interaction with the Gag precursor, indicating that this presence in the core of the mature virions is mainly required for optimal...

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PMID: 24744753
DOI: 10.3389/fmicb.2014.00127

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