Article
HIV1-viral protein R (Vpr) mutations: associated phenotypes and relevance for clinical pathologies.
Reviews in medical virology - 1 Sept 2016
Soares Rui, Rocha Graça, Meliço-Silvestre António, Gonçalves Teresa
Abstract excerpt
Over the last 30 years, research into HIV has advanced the knowledge of virus genetics and the development of efficient therapeutic strategies. HIV-1 viral protein R (Vpr) is a specialized and multifunctional protein that plays important roles at multiple stages of the HIV-1 viral life cycle. This protein interacts with a number of cellular and viral proteins and with multiple activities including nuclear...
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