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Single-cell RNA sequencing of OSCC primary tumors and lymph nodes reveals distinct origin and phenotype of fibroblasts

2024-01-30

Abstract excerpt

<title>Abstract</title> <p>Desmoplasia in fibroblasts within metastatic lymph nodes (MLNs) serves as an indicator of extranodal extension (ENE), which is a critical determinant of distant metastasis and mortality in oral squamous cell carcinoma (OSCC). However, systematic studies on fibroblasts in MLNs are lacking. Therefore, this study investigated and characterized the differences in phenotype, function, and or...

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Literature Corpus work
bcb64af9-e516-58d2-9270-d10df280a2c9
DOI
10.21203/rs.3.rs-3862426/v1
Open publication

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Single-cell RNA sequencing of OSCC primary tumors and lymph nodes reveals distinct origin and phenotype of fibroblastsDOI 10.21203/rs.3.rs-3862426/v1
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