Article

Multiomics profiling reveals excessive fibroblast activation and collagen deposition are associated with poor prognosis in desmoid tumors

2026-06-01

Abstract excerpt

<title>Abstract</title> <p> <bold>Backgroud</bold> Desmoid tumors (DT) is a rare locally aggressive soft tissue tumor of fibroblastic origin, exhibiting unique biological behavior characterized by spontaneous shrinkage or enlargement. It demonstrates high recurrence rates after surgical resection and lacks of prognostic biomarkers. <bold>Methods</bold> A total of 102 paraffin-embedded tissue samples from 88 s...

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Literature Corpus work: 71e9e22d-1bbe-55f2-a522-4b25246d8191
DOI: 10.21203/rs.3.rs-9585107/v1

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