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CRISPR-cas9 Screening Identified Lethal Genes Enriched in Hippo Kinase Pathway and of Prognosis Significance in primary Low-grade Glioma

2022-10-11

Abstract excerpt

<title>Abstract</title> <p>Background Lethal genes in low-grade gliomas (LGGs) may have an essential prognostic significance and therefore need to be systematically analyzed. The purpose of this study is to analyze essential genes correlated with cell survival by evaluating CRISPR-cas9 screening data, leading to the identification of novel treatment targets for patients. Methods In this study, genes related to...

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Literature Corpus work
bca31692-093e-5390-9fa0-65c6750c9654
DOI
10.21203/rs.3.rs-2116553/v1
Open publication

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CRISPR-cas9 Screening Identified Lethal Genes Enriched in Hippo Kinase Pathway and of Prognosis Significance in primary Low-grade GliomaDOI 10.21203/rs.3.rs-2116553/v1
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