Article

Neurodevelopmental wiring deficits in the Ts65Dn mouse model of Down syndrome

2019-09-26

Abstract excerpt

Down syndrome is the most common genetic cause of intellectual disability and occurs due to the trisomy of human chromosome 21. Adolescent and adult brains from humans with Down syndrome exhibit various neurological phenotypes including a reduction in the size of the corpus callosum, hippocampal commissure and anterior commissure. However, it is unclear when and how these interhemispheric connectivity defects aris...

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Literature Corpus work: bc9a159a-ffaf-536a-b50b-c663b7a32d43
DOI: 10.1101/784314

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