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Article

Understanding mental retardation in Down's syndrome using trisomy 16 mouse models

1 Jun 2003

Abstract excerpt

Mental retardation in Down's syndrome, human trisomy 21, is characterized by developmental delays, language and memory deficits and other cognitive abnormalities. Neurophysiological and functional information is needed to understand the mechanisms of mental retardation in Down's syndrome. The trisomy mouse models provide windows into the molecular and developmental effects associated with abnormal chromosome...

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Identifiers

PMID: 12931790
DOI: 10.1034/j.1601-183x.2003.00024.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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