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Article

Single‐cell profiles reveal distinctive immune response in atopic dermatitis in contrast to psoriasis

20 Aug 2022

Abstract excerpt

BACKGROUND: Understanding the complex orchestrated inflammation in atopic dermatitis (AD), one of the most common chronic inflammatory diseases worldwide, is essential for therapeutic approaches. However, a comparative analysis on the single-cell level of the inflammation signatures correlated with the severity is missing so far. METHODS: We applied single-cell RNA and T-cell receptor (TCR) sequencing on immune...

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PMID: 35986602
DOI: 10.1111/all.15486

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