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Article

Cell-type-specific transcriptome architecture underlying the establishment and exacerbation of systemic lupus erythematosus

2022-01-16

Abstract excerpt

Systemic lupus erythematosus (SLE) is a complex and heterogeneous autoimmune disease involving multiple immune cells. A major hurdle to the elucidation of SLE pathogenesis is our limited understanding of dysregulated gene expression linked to various clinical statuses with a high cellular resolution. Here, we conducted a large-scale transcriptome study with 6,386 RNA sequencing data covering 27 immune cell types f...

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Literature Corpus work
bc68d82d-9ea0-53ee-ba83-f130ed6c6af3
DOI
10.1101/2022.01.12.22269137
Open publication

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Cell-type-specific transcriptome architecture underlying the establishment and exacerbation of systemic lupus erythematosusDOI 10.1101/2022.01.12.22269137
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