Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel potential lncRNA biomarker in B cells indicates essential pathogenic pathway activation in patients with SLE

1 Apr 2024

Abstract excerpt

OBJECTIVES: Systemic lupus erythematosus (SLE) is a highly heterogeneous disease, and B cell abnormalities play a central role in the pathogenesis of SLE. Long non-coding RNAs (lncRNAs) have also been implicated in the pathogenesis of SLE. The expression of lncRNAs is finely regulated and cell-type dependent, so we aimed to identify B cell-expressing lncRNAs as biomarkers for SLE, and to explore their ability to...

Topics

Join the communities discussing this publication.

Cancer-related molecular mechanisms research
interferon and immune responses
Systemic Lupus Erythematosus Research

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38599668
DOI: 10.1136/lupus-2023-001065

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel potential lncRNA biomarker in B cells indicates essential pathogenic pathway activation in patients with SLEPMID 38599668Read ↗

Integrated Transcriptome Profiling Revealed That Elevated Long Non-Coding RNA-AC007278.2 Expression Repressed CCR7 Transcription in Systemic Lupus ErythematosusSemantic proximity Read ↗

Key genes and functional coexpression modules involved in the pathogenesis of systemic lupus erythematosusSemantic proximity Read ↗

Single Cell and Transcriptomic Analysis of Regulatory Mechanisms of Key Genes in Systemic Lupus ErythematosusSemantic proximity Read ↗

B cell subsets-related biomarkers and molecular pathways for systemic lupus erythematosus by transcriptomics analysesSemantic proximity Read ↗

Novel Long Non-coding RNA Expression Profile of Peripheral Blood Mononuclear Cells Reveals Potential Biomarkers and Regulatory Mechanisms in Systemic Lupus ErythematosusSemantic proximity Read ↗

Full high-throughput sequencing analysis of differences in expression profiles of long noncoding RNAs and their mechanisms of action in systemic lupus erythematosusSemantic proximity Read ↗

Screening biomarkers for systemic lupus erythematosus based on single-cell and bulk RNA sequencingSemantic proximity Read ↗

Identification of Key Genes in Systemic Lupus Erythematosus through integrated bioinformaticsSemantic proximity Read ↗

SLE-Diseaseome: A Comprehensive Meta-Database of Systemic Lupus Erythematosus Relevant Functional PathwaysSemantic proximity Read ↗

Identification of key interferon-stimulated genes for indicating the condition of patients with systemic lupus erythematosusSemantic proximity Read ↗

Genome-Wide Identification of Cell Type-Specific Susceptibility Genes for SLE Through the Analysis of RNA Modification-Associated SNPs.Semantic proximity Read ↗

Transcriptome sequencing reveals novel molecular features of SLE severitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.