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Unraveling transcriptomic signatures and dysregulated pathways in systemic lupus erythematosus across disease states

13 May 2024

Abstract excerpt

OBJECTIVES: This study aims to elucidate the transcriptomic signatures and dysregulated pathways in patients with Systemic Lupus Erythematosus (SLE), with a particular focus on those persisting during disease remission. METHODS: We conducted bulk RNA-sequencing of peripheral blood mononuclear cells (PBMCs) from a well-defined cohort comprising 26 remission patients meeting the Low Lupus Disease Activity State...

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PMID: 38741185
DOI: 10.1186/s13075-024-03327-4

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