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Integrating functional genomics and proteomics identifies Folate Carrier SLC19A1 as a predictor of pralatrexate sensitivity in T-cell lymphoma

2025-10-09

Abstract excerpt

<h4>ABSTRACT</h4> Cancer therapies are typically effective in subsets of patients, reflecting the molecular diversity of cancers and motivating the need for predictive biomarkers of response. Biomarker-guided therapy is increasingly useful in oncology, yet biomarker discovery remains complicated by the large number of molecular features that make it difficult to distinguish causal determinants from spurious assoc...

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Literature Corpus work
bc59c1b6-8012-5fb2-a328-d13794aeda7f
DOI
10.1101/2025.10.08.681217
Open publication

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Integrating functional genomics and proteomics identifies Folate Carrier SLC19A1 as a predictor of pralatrexate sensitivity in T-cell lymphomaDOI 10.1101/2025.10.08.681217
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