Article
Protein quantitative trait loci identify novel candidates modulating cellular response to chemotherapy.
PLoS genetics - 1 Apr 2014
Stark Amy L, Hause Ronald J, Gorsic Lidija K, Antao Nirav N, Wong Shan S, Chung Sophie H, Gill Daniel F, Im Hae K, Myers Jamie L, White Kevin P, Jones Richard Baker, Dolan M Eileen
Abstract excerpt
Annotating and interpreting the results of genome-wide association studies (GWAS) remains challenging. Assigning function to genetic variants as expression quantitative trait loci is an expanding and useful approach, but focuses exclusively on mRNA rather than protein levels. Many variants remain...
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