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Article

Advances in Genomics for Drug Development.

Genes - 15 Aug 2020

Spreafico Roberto, Soriaga Leah B, Grosse Johannes, Virgin Herbert W, Telenti Amalio

Abstract excerpt

Drug development (target identification, advancing drug leads to candidates for preclinical and clinical studies) can be facilitated by genetic and genomic knowledge. Here, we review the contribution of population genomics to target identification, the value of bulk and single cell gene expression analysis for understanding the biological relevance of a drug target, and genome-wide CRISPR editing for the...

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Identifiers

PMID: 32824125
DOI: 10.3390/genes11080942
PMCID: PMC7465049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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