Article

Modelling glioblastoma tumour-host cell interactions using adult brain organotypic slice co-culture

2017-07-21

Abstract excerpt

Glioblastoma (GBM) is an aggressive incurable brain cancer. The cells that fuel the growth of tumours resemble neural stem cells found in the developing and adult mammalian forebrain. These are referred to as GBM stem cells (GSCs). Similar to neural stem cells, GSCs exhibit a variety of phenotypic states: dormant, quiescent, proliferative and differentiating. How environmental cues within the brain influence these...

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Literature Corpus work: bc400498-9673-55c6-9b33-1e9eca082a39
DOI: 10.1101/166967

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