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Glioblastoma and cerebral organoids: development and analysis of an in vitro model for glioblastoma migration

6 Feb 2023

Abstract excerpt

It is currently challenging to adequately model the growth and migration of glioblastoma using two-dimensional (2D) in vitro culture systems as they quickly lose the original, patient-specific identity and heterogeneity. However, with the advent of three-dimensional (3D) cell cultures and human-induced pluripotent stem cell (iPSC)-derived cerebral organoids (COs), studies demonstrate that the glioblastoma-CO...

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PMID: 36744875
DOI: 10.1002/1878-0261.13389

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