Article
Cortical and subventricular zone glioblastoma-derived stem-like cells display different molecular profiles and differential in vitro and in vivo properties.
Annals of surgical oncology - 1 Jul 2012
Tchoghandjian Aurélie, Baeza-Kallee Nathalie, Beclin Christophe, Metellus Philippe, Colin Carole, Ducray François, Adélaïde José, Rougon Geneviève, Figarella-Branger Dominique
Abstract excerpt
BACKGROUND: Cellular self-renewal capacity in glioblastomas is heterogeneous, with only stem-like cells having this property. These cells generate a specific tumor phenotype, but no link with tumor location or molecular characteristics has ever been made. METHODS: Two cells lines, established fro...
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