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Regulatory effects on virulence and phage susceptibility revealed by <i>sdiA</i> mutation in <i>Klebsiella pneumoniae</i>

2024-09-27

Abstract excerpt

The World Health Organization has identified multi-drug resistant (MDR) Klebsiella pneumoniae strains as the highest priority in 2024. SdiA, a LuxR-like quorum sensing (QS) receptor that responds to N- acyl-homoserine lactones (AHLs), exerts a substantial regulatory influence on the virulence of numerous Gram-negative bacteria. The function of this receptor in the virulence of K. pneumoniae remains uncertain. N...

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Literature Corpus work
bc1398ed-957a-59fd-83e9-8f758110e4e7
DOI
10.1101/2024.09.27.615489
Open publication

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