Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phage resistance bidirectionally altered antibiotic susceptibility in Klebsiella pneumoniae via galE mutation.

International journal of antimicrobial agents - 1 Apr 2026

Wahid Braira, Nang Sue C, Zhao Jinxin, Kho Zhi Ying, Han Meiling, Yu Heidi Hoi-Yin, Wickremasinghe Hasini, Bergen Phillip J, Aslam Saima, Schooley Robert T, Li Jian

Abstract excerpt

OBJECTIVE: Multidrug-resistant (MDR) Gram-negative bacteria, particularly Klebsiella pneumoniae, represent a significant threat to global health. Given the shortage of new antibiotics, bacteriophages (phages) offer a promising alternative. Understanding bacteria-phage interactions and resistance mechanisms is vital for optimising phage therapy. We aimed to investigate the resistance mechanism of an MDR clinical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bacteriophages

Share to Drug Resistance, Multiple, Bacterial

Share to Klebsiella pneumoniae

Share to Lipopolysaccharides

Share to Microbial Sensitivity Tests

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 41662980
DOI: 10.1016/j.ijantimicag.2026.107738
PMCID: PMC13420019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phage resistance bidirectionally altered antibiotic susceptibility in Klebsiella pneumoniae via galE mutation.PMID 41662980Read ↗

Phage-mediated virulence loss and antimicrobial susceptibility in carbapenem-resistant Klebsiella pneumoniae.Semantic proximity Read ↗

Phage resistance in Klebsiella pneumoniae and bidirectional effects impacting antibiotic susceptibility.Semantic proximity Read ↗

Diversified repertoire of phage resistance in <i>Klebsiella pneumoniae</i> and bidirectional steering effects impacting antibiotic susceptibilitySemantic proximity Read ↗

Bacteriophage-induced outer membrane protein remodelling drives the phenotypic switching and antibiotic re-sensitization in Klebsiella pneumoniae.Semantic proximity Read ↗

Phage Henu12-resistant mutant derives fitness trade-offs in Shigella dysenteriae.Semantic proximity Read ↗

PHENOTYPIC CHARACTERIZATION OF FIVE PHAGES ACTIVE AGAINST ANTIBIOTIC-RESISTANT KLEBSIELLA PNEUMONIAE.Semantic proximity Read ↗

Bacteriophage therapy: a possible alternative therapy against antibiotic-resistant strains of Klebsiella pneumoniaeSemantic proximity Read ↗

Harnessing Lytic Phages for Biofilm Control in Carbapenem-Resistant <i>Klebsiella pneumoniae</i> Causing Urinary Tract InfectionSemantic proximity Read ↗

Bacteriophages of <i>Klebsiella</i> spp., their diversity and potential therapeutic usesSemantic proximity Read ↗

Characterization of a Klebsiella pneumoniae mutant strain wGF 1-2 with attenuated virulence, altered morphology, and reduced biofilm formation.Semantic proximity Read ↗

Investigating the phenotypic alterations associated with hypermucoviscous hypervirulent Klebsiella pneumoniae during phage resistance development.Semantic proximity Read ↗

Genomic characterization of a lytic bacteriophage targeting multidrug resistant <i>Klebsiella pneumoniae</i> from hospital sewage in Dhaka, BangladeshSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.