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Article

Impact of LuxS on virulence and pathogenicity in Klebsiella pneumoniae exhibiting varied mucoid phenotypes.

Infection and immunity - 12 Mar 2024

Tang Miran, Zhao Deyi, Zhang Ying, Qian Changrui, Chen Huale, Chen Lijiang, Ye Jianzhong, Zhou Tieli

Abstract excerpt

How the LuxS/AI-2 quorum sensing (QS) system influences the pathogenicity of K. pneumoniae is complicated by the heterogeneity of the bacterial mucoid phenotypes. This study aims to explore the LuxS-mediated regulation of the pathogenicity of K. pneumoniae with diverse mucoid phenotypes, including hypermucoid, regular-mucoid, and nonmucoid. The wild-type, luxS knockout, and complemented strains of three K....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38358274
DOI: 10.1128/iai.00012-24
PMCID: PMC10929404

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