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Article

Monoallelic antigen expression in trypanosomes requires a stage-specific transcription activator

2021-05-06

Abstract excerpt

Monoallelic expression of a single gene family member underpins a molecular “arms race” between many pathogens and their host, through host monoallelic immunoglobulin and pathogen monoallelic antigen expression. In Trypanosoma brucei , a single, abundant, variant surface glycoprotein (VSG) covers the entire surface of the bloodstream parasite 1 and monoallelic VSG transcription underpins their archetypal example...

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Literature Corpus work
bc0fbc22-f7c0-52da-ac2c-4fe6900ed447
DOI
10.1101/2021.05.06.442931
Open publication

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Monoallelic antigen expression in trypanosomes requires a stage-specific transcription activatorDOI 10.1101/2021.05.06.442931
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