Article

<i>Mirage2</i> ’s high-quality spliced protein-to-genome mappings produce accurate multiple-sequence alignments of isoforms

2022-12-16

Abstract excerpt

The organization of homologous protein sequences into multiple sequence alignments (MSAs) is a cornerstone of modern analysis of proteins. Recent focus on the importance of alternatively-spliced isoforms in disease and cell biology has highlighted the need for MSA software that can appropriately account for isoforms and the exon-length insertions or deletions that isoforms may have relative to each other. We previ...

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Literature Corpus work: bc0723e0-3890-5389-8424-b6e62d42936f
DOI: 10.1101/2022.12.14.520492

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