Article
IsoAligner: dynamic mapping of amino acid positions across protein isoforms
2022-03-31
Abstract excerpt
Aligning protein isoform sequences is often performed in cancer diagnostics to homogenise mutation annotations from different diagnostic assays. However, most alignment tools are fitted for homologous sequences, leading often to alignments of non-identical exonic regions. Here, we present the interactive alignment webservice IsoAligner for exact mapping of exonic protein subsequences. The tool uses a customized Ne...
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Identifiers and source
- Literature Corpus work
- 9718934e-8fae-5649-998e-69ee5a476de7
- DOI
- 10.12688/f1000research.76154.1