Article

Highly accurate isoform identification for the human transcriptome

2022-06-09

Abstract excerpt

We explore a new hypothesis in genome annotation, namely whether computationally predicted protein structures can help to identify which of multiple possible gene isoforms represents a functional protein product. Guided by structure predictions, we evaluated over 140,000 isoforms of human protein-coding genes assembled from over 10,000 RNA sequencing experiments across many human tissues. We illustrate our new met...

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Literature Corpus work: fad0bb3c-9d03-54ba-968d-c7b9a0f7a5a4
DOI: 10.1101/2022.06.08.495354

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