Article

Colon Cancer: A Teleonomic Information Model of Carcinogenesis

2026-06-17

Abstract excerpt

The somatic mutation theory (SMT) has dominated cancer research for decades, yet The Cancer Genome Atlas (TCGA) data reveal that only 40% of colon cancers harbor KRAS mutations. This paper proposes a conceptual shift: carcinogenesis is not solely a genetic disease but an informatic disorder. Drawing on Prigogine’s thermodynamics, transcriptomic entropy, and the Woodward–Kharkevich (W–K) teleonomic information meas...

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Literature Corpus work: bbe21bf8-5b29-5f7a-9efc-a26f1d868611
DOI: 10.20944/preprints202606.1318.v1

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