Article

Replication in the presence of dengue convalescent serum impacts Zika virus neutralization sensitivity and fitness

2022-12-21

Abstract excerpt

Flaviviruses like dengue virus (DENV) and Zika virus (ZIKV) are mosquito-borne viruses that cause febrile, hemorrhagic, and neurological diseases in humans, resulting in 400 million infections annually. Due to their co-circulation in many parts of the world, flaviviruses must replicate in the presence of pre-existing adaptive immune responses targeted at serologically closely related pathogens, which can provide p...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bbd76753-3f7f-5d2b-b729-bbc61eaa72f4
DOI: 10.1101/2022.12.21.521484

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Replication in the presence of dengue convalescent serum impacts Zika virus neutralization sensitivity and fitnessDOI 10.1101/2022.12.21.521484Read

A Zika virus mutation enhances transmission potential and confers escape from protective dengue virus immunity.Semantic proximity Read

The Incompetence of Mosquitoes-Can Zika Virus Be Adapted To Infect Culex tarsalis Cells?Semantic proximity Read

An accumulated mutation gained in mosquito cells enhances Zika virus virulence and fitness in mice.Semantic proximity Read

Genomic and phenotypic analyses suggest moderate fitness differences among Zika virus lineagesSemantic proximity Read

Principles of dengue virus evolvability derived from genotype-fitness maps in human and mosquito cells.Semantic proximity Read

The effect of single mutations in Zika virus envelope on escape from broadly neutralizing antibodiesSemantic proximity Read

The effect of single mutations in Zika virus envelope on escape from broadly neutralizing antibodies.Semantic proximity Read

Adaptation to host cell environment during experimental evolution of Zika virusSemantic proximity Read

Adaptation to host cell environment during experimental evolution of Zika virusSemantic proximity Read

Dengue Virus Antibodies Enhance Zika Virus InfectionSemantic proximity Read

Emergence of Zika virus: Direct reversion of mutations and fitness restoration prior to spread to the AmericasSemantic proximity Read

Adaptation to host cell environment during experimental evolution of Zika virusSemantic proximity Read