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Article

Adaptation to host cell environment during experimental evolution of Zika virus

2020-12-28

Abstract excerpt

Zika virus (ZIKV) infection can cause important developmental and neurological defects in Humans. Type I/III interferon responses control ZIKV infection and pathological processes, yet the virus has evolved various mechanisms to defeat these host responses. Here, we established a pipeline to delineate at high-resolution the genetic evolution of ZIKV in a controlled host cell environment. We uncovered that serially...

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Identifiers and source

Literature Corpus work
00d97492-3b33-5e6d-ab24-487c27a865a3
DOI
10.1101/2020.12.28.424577
Open publication

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Adaptation to host cell environment during experimental evolution of Zika virusDOI 10.1101/2020.12.28.424577
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