Article

Conidial melanin of the human pathogenic fungus <i>Aspergillus fumigatus</i> disrupts cell autonomous defenses in amoebae

2019-08-09

Abstract excerpt

The human pathogenic fungus Aspergillus fumigatus is a ubiquitous saprophyte that causes fatal infections in immunocompromised individuals. Following inhalation, conidia are ingested by innate immune cells and can arrest phagolysosome maturation. How such general virulence traits could have been selected for in natural environments is unknown. Here, we used the model amoeba Dictyostelium discoideum to follow the...

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Literature Corpus work: bbd5f4bf-af37-5559-b365-5a4501848e00
DOI: 10.1101/730879

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