Article

Think zinc: Role of zinc poisoning in the intraphagosomal killing of bacteria by the amoeba <i>Dictyostelium</i>

2018-06-27

Abstract excerpt

Professional phagocytes have developed an extensive repertoire of autonomous immunity strategies to ensure killing of bacteria. Besides phagosome acidification and the generation of reactive oxygen species, deprivation of nutrients and the lumenal accumulation of toxic metals are essential to kill ingested bacteria or inhibit growth of intracellular pathogens. We use the soil amoeba Dictyostelium discoideum , a p...

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Literature Corpus work: 4b9caa8a-b102-5129-8034-efedb2efe048
DOI: 10.1101/356949

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