Article

Phagocytic podosomes enable efficient uptake of <i>Candida auris</i> by primary human macrophages

2025-09-15

Abstract excerpt

The yeast Candida auris is an emerging pathogen of steadily increasing importance. Understanding the molecular mechanisms of C. auris uptake and intracellular processing by immune cells such as macrophages is thus critical for counteracting the spreading of respective infections. Here, we show that phagocytosis of C. auris cells by primary human macrophages involves the formation of dot-like F-actin-rich struct...

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Literature Corpus work: 4ab7f85f-fd80-5890-8187-c34d76ca3ab7
DOI: 10.1101/2025.09.13.676015

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