Article

Macrophage phagocytosis of <i>Coccidioides</i> promotes its differentiation into the parasitic form

2025-10-05

Abstract excerpt

<h4>ABSTRACT</h4> Coccidioides is an endemic fungus that is increasing in prevalence and can cause life threatening disease in otherwise immunocompetent people. In the environment the spores (arthroconidia) develop into hyphae, yet when they are inhaled by a mammalian host, they develop into a unique form called the spherule. The transition to spherule can be triggered in vitro with elevated temperatures and hig...

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Literature Corpus work: f70f739f-7d78-56bf-bb3d-1d77511f5964
DOI: 10.1101/2025.10.05.680493

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