Virulence determinants of the human pathogenic fungus <scp> <i>A</i> </scp> <i>spergillus fumigatus</i> protect against soil amoeba predation

Abstract excerpt

Filamentous fungi represent classical examples for environmentally acquired human pathogens whose major virulence mechanisms are likely to have emerged long before the appearance of innate immune systems. In natural habitats, amoeba predation could impose a major selection pressure towards the acquisition of virulence attributes. To test this hypothesis, we exploited the amoeba Dictyostelium discoideum to study...

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