Article

Fungal infection drives metabolic reprogramming in epithelial cells via aerobic glycolysis and an alternative TCA cycle shunt

2022-11-01

Abstract excerpt

<title>Abstract</title> Immunometabolic changes induced by the fungal pathobiont <italic>Candida albicans</italic> drive complex responses in innate immune cells. However, whether and how <italic>C. albicans</italic> causes remodelling of oral epithelial cell metabolism is unclear. Here, we use <italic>in vitro</italic> experiments and patient biopsies to demonstrate that oral epithelial cells (OECs) undergo a...

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Literature Corpus work: bbbd6dee-ef9b-561c-81b7-1b8e447063e9
DOI: 10.21203/rs.3.rs-2159406/v1

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