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High-Throughput Antibody Neutralization Screening in Massively Parallel Droplet Arrays

2025-02-04

Abstract excerpt

Neutralizing antibodies provide rapid immune defense against infectious diseases, but are difficult to discover at scale because neutralization assays require live reporter cells and soluble monoclonal antibodies. Here we report Droplet Reporter Cell Testing for Neutralization (DrReCT-Neutralization) to screen antibody gene libraries for their ability to neutralize viral infections. We established the necessary en...

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Literature Corpus work
bbb5cede-179b-535b-865f-5eb98b73c356
DOI
10.1101/2025.01.31.635965
Open publication

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High-Throughput Antibody Neutralization Screening in Massively Parallel Droplet ArraysDOI 10.1101/2025.01.31.635965
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