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Article

Single-cell deep phenotyping of IgG-secreting cells for high-resolution immune monitoring.

Nature biotechnology - 1 Oct 2017

Eyer Klaus, Doineau Raphaël C L, Castrillon Carlos E, Briseño-Roa Luis, Menrath Vera, Mottet Guillaume, England Patrick, Godina Alexei, Brient-Litzler Elodie, Nizak Clément, Jensen Allan, Griffiths Andrew D, Bibette Jérôme, Bruhns Pierre, Baudry Jean

Abstract excerpt

Studies of the dynamics of the antibody-mediated immune response have been hampered by the absence of quantitative, high-throughput systems to analyze individual antibody-secreting cells. Here we describe a simple microfluidic system, DropMap, in which single cells are compartmentalized in tens of thousands of 40-pL droplets and analyzed in two-dimensional droplet arrays using a fluorescence relocation-based...

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PMID: 28892076
DOI: 10.1038/nbt.3964

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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