Article

Characterization of the Xeno-GVHD Response Generated by Lung Cancer Patient PBMCs in NSG-SGM3 Mice

2024-03-28

Abstract excerpt

<title>Abstract</title> <p>Humanized mouse models based on PBMC transplants have become a critical preclinical platform for NSCLC investigation. However, the emergence of xeno-GVHD poses challenges that need clarification. In this study, we explore clinical and molecular aspects of xeno-GVHD induced by NSCLC patient PBMCs compared to healthy donors in the novel NSG-SGM3 mice. PBMCs from NSCLC patients and healthy...

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Literature Corpus work: bb896900-60db-5102-aa92-40a82212e03e
DOI: 10.21203/rs.3.rs-4086903/v1

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