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Article

Xenogeneic graft-versus-host-disease in NOD-scid IL-2Rγnull mice display a T-effector memory phenotype.

PloS one - 1 Jan 2012

Ali Niwa, Flutter Barry, Sanchez Rodriguez Robert, Sharif-Paghaleh Ehsan, Barber Linda D, Lombardi Giovanna, Nestle Frank O

Abstract excerpt

The occurrence of Graft-versus-Host Disease (GvHD) is a prevalent and potentially lethal complication that develops following hematopoietic stem cell transplantation. Humanized mouse models of xenogeneic-GvHD based upon immunodeficient strains injected with human peripheral blood mononuclear cells (PBMC; "Hu-PBMC mice") are important tools to study human immune function in vivo. The recent introduction of...

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Source

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Identifiers

PMID: 22937164
DOI: 10.1371/journal.pone.0044219
PMCID: PMC3429415

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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