Article

Cardiac atrophy, dysfunction, and metabolic impairments: a cancer-induced heart failure phenotype

2023-10-02

Abstract excerpt

<h4>ABSTRACT</h4> Muscle atrophy and weakness are prevalent features of cancer. While extensive research has characterized skeletal muscle wasting in cancer cachexia, limited studies have investigated how cardiac structure and function are affected by therapy-naïve cancer. In cell-based models of orthotopic, syngeneic epithelial ovarian cancer (EOC) and pancreatic ductal adenocarcinoma (PDAC), and a patient-deriv...

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Literature Corpus work: bb534d99-ca04-5b92-ae51-b2a9bfd0ec1d
DOI: 10.1101/2023.09.30.560250

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