Article

Integrative study of skeletal muscle mitochondrial dysfunction in a murine pancreatic cancer-induced cachexia model

2022-12-29

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Aims</h4> Pancreatic Ductal AdenoCarcinoma (PDAC), the most common pancreatic cancer, is a deadly cancer, often diagnosed late and resistant to current therapies. PDAC patients are frequently affected by cachexia characterized by muscle mass and strength loss (sarcopenia) contributing to patient frailty and poor therapeutic response. The objective of this work was to investigate the mechani...

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Literature Corpus work: 5aa60d86-d7b5-59cb-aa78-cd74dd1c7bee
DOI: 10.1101/2022.12.28.522098

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